Jan Rehwinkel

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence

Selene Glück, Baptiste Guey, Muhammet F. Gülen et al. · Nature Cell Biology · 2017 · 1.1K citations · Full text

Chromatin, Innate Immune Sensing, Cytosolic Chromatin Fragments +10

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

Isabelle Behm‐Ansmant, Jan Rehwinkel, Tobias Doerks et al. · Genes & Development · 2006 · 1K citations · Full text

Chromatin, Transcriptional Regulation, Systems Biology +14

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

Ashish Dhir, Somdutta Dhir, Lukasz S. Borowski et al. · Nature · 2018 · 597 citations · Full text

Viral Replication, Immunology, Antiviral Response +2

RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

Jan Rehwinkel, Choon Ping Tan, Delphine Goubau et al. · Cell · 2010 · 592 citations · Full text

Viral Replication, Molecular Virology, Pathogenesis +4

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates

Delphine Goubau, Martin Schlee, Safia Deddouche et al. · Nature · 2014 · 551 citations · Full text

Antiviral Immunity, Immunology, Antiviral Response +4