Martin Schlee

5'-Triphosphate RNA Is the Ligand for RIG-I

Veit Hornung, Jana M. Ellegast, Sarah Kim-Hellmuth et al. · Science · 2006 · 2.4K citations

Viral Replication, Systems Biology, Engineering +12

Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7

Veit Hornung, Margit Guenthner‐Biller, Carole Bourquin et al. · Nature Medicine · 2005 · 1.2K citations · Full text

Innate Immune System, Immunology, Immune Regulation +16

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

Martin Schlee, Andreas Roth, Veit Hornung et al. · Immunity · 2009 · 769 citations · Full text

Virus Structure, Viral Replication, Negative-strand Virus +9

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates

Delphine Goubau, Martin Schlee, Safia Deddouche et al. · Nature · 2014 · 551 citations · Full text

Antiviral Immunity, Immunology, Antiviral Response +4

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production

Hendrik Poeck, Michael Bscheider, Katrin Finger et al. · Nature Immunology · 2009 · 510 citations

Inflammation, Rig-i Results, Viral Pathogenesis +11