Jana M. Ellegast

5'-Triphosphate RNA Is the Ligand for RIG-I

Veit Hornung, Jana M. Ellegast, Sarah Kim-Hellmuth et al. · Science · 2006 · 2.4K citations

Viral Replication, Systems Biology, Engineering +12

Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in mice

Yasuyuki Saito, Jana M. Ellegast, Anahita Rafiei et al. · Blood · 2016 · 82 citations · Full text

Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33

Ninel Azoitei, Christopher M. Hoffmann, Jana M. Ellegast et al. · The Journal of Experimental Medicine · 2012 · 78 citations · Full text

Systems Biology, Kras Mutant Tumors, Hsp90 Inhibitors +13

RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia

Saskia Rudat, Anja Pfaus, Ya‐Yun Cheng et al. · Leukemia · 2018 · 64 citations

Hematological Malignancy, Cell Autophagy, Mixed-phenotype Acute Leukemia +11

Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2

Jonathan R. LaRochelle, Michelle Fodor, Jana M. Ellegast et al. · Bioorganic & Medicinal Chemistry · 2017 · 52 citations · Full text

Biochemistry, Medicine, Receptor Tyrosine Kinase +5