TDP‐43 regulates its mRNA levels through a negative feedback loop

Youhna M. Ayala, Laura De Conti, S. Eréndira Avendaño‐Vázquez, +8

The EMBO Journal

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

Ashish Dhir, Somdutta Dhir, Lukasz S. Borowski, +15

Nature

Viral ReplicationImmunologyAntiviral ResponseVirologyMedicine

Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection

S. Eréndira Avendaño‐Vázquez, Ashish Dhir, Sara Bembich, +3

Genes & Development

cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing

Carolina Uggenti, Alice Lepelley, Marine Depp, +53

Nature Genetics

ChromatinInborn ErrorsChromatin RemodelingGeneticsCgas-mediated Induction +8

RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination

Claudia Ribeiro de Almeida, Somdutta Dhir, Ashish Dhir, +4

Molecular Cell

Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence

Takayuki Nojima, Michael Tellier, Jonathan Foxwell, +6

Molecular Cell

Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs

Ashish Dhir, Somdutta Dhir, Catherine L. Jopling

Nature Structural & Molecular Biology

Transcriptional TerminationTranscriptional RegulationNatural SciencesMolecular BiologyLong Non-coding Rna +6

Enhanced cGAS-STING–dependent interferon signaling associated with mutations in ATAD3A

Alice Lepelley, Erika Della Mina, Erika Van Nieuwenhove, +27

The Journal of Experimental Medicine

MitophagyGeneticsImmunologyCell DeathInterferon Genes +28

RNA structure is a key regulatory element in pathological ATM and CFTR pseudoexon inclusion events

Emanuele Buratti, Ashish Dhir, Marzena Anna Lewandowska, +1

Nucleic Acids Research

Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo

Aleksandra Pajak, Isabelle Laine, Paula Clemente, +10

PLoS Genetics

Mitochondrial MrnasMitophagySystems BiologyMitochondrial BiogenesisMitochondrial Function +12