Daniel C. Bensen

Comparative Genomic Analysis of Archaeal Genotypic Variants in a Single Population and in Two Different Oceanic Provinces

Oded Béjà, Eugene V. Koonin, L. Aravind et al. · Applied and Environmental Microbiology · 2002 · 171 citations · Full text

Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity

Leslie W. Tari, Michael Trzoss, Daniel C. Bensen et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 115 citations

Medicinal Chemistry, Drug Target, Dna Gyrase B +10

Tricyclic GyrB/ParE (TriBE) Inhibitors: A New Class of Broad-Spectrum Dual-Targeting Antibacterial Agents

Leslie W. Tari, Xiaoming Li, Michael Trzoss et al. · PLoS ONE · 2013 · 103 citations · Full text

Topoisomerase Complexes, Important Pathogens, Molecular Biology +17

Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: Development of inhibitors with broad spectrum, Gram-negative antibacterial activity

Micheal Trzoss, Daniel C. Bensen, Xiaoming Li et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 80 citations

Inhibitory Activity, Biochemistry, Medicine +11

Distinguishing On-Target versus Off-Target Activity in Early Antibacterial Drug Discovery Using a Macromolecular Synthesis Assay

Mark L. Cunningham, Bryan P. Kwan, Kirk Nelson et al. · SLAS DISCOVERY · 2013 · 38 citations · Full text

Drug Target, Bioorganic Chemistry, Antimicrobial Chemotherapy +20