Concepedia

Author

Takeshi Wakasa

Taiho Pharmaceutical (Japan)ORCID

Also Known As

T. Wakasa, Takeshi Wakasa

75

Publications

496

Citations

13

H-Index

44

Concepts

All Affiliations

Taiho Pharmaceutical (Japan)Kyushu UniversityGifu Pharmaceutical UniversityKyushu Central Hospital of the Mutual Aid Association of Public School TeachersHokkaido University
TW

About

Takeshi Wakasa is an author at Taiho Pharmaceutical (Japan) specializing in medicine, cell biology, and cancer research.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

6

6

221

2

Cell Biology

3

3

121

3

Natural Sciences

1

1

32

4

Biochemistry

1

1

32

5

Biomolecular Engineering

1

1

32

Takeshi Wakasa

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12

Publications

340

Citations

12

H-Index

YearCitations

Tissue-Restricted Expression of Nrf2 and Its Target Genes in Zebrafish with Gene-Specific Variations in the Induction Profiles

Hitomi Nakajima, Yaeko Nakajima‐Takagi, Tadayuki Tsujita,

PLoS ONE

2011

70

1,2,3-Triazole-Containing Uracil Derivatives with Excellent Pharmacokinetics as a Novel Class of Potent Human Deoxyuridine Triphosphatase Inhibitors

Hitoshi Miyakoshi, Seiji Miyahara, Tatsushi Yokogawa,

Journal of Medicinal Chemistry

2012

55

dUTPase inhibition confers susceptibility to a thymidylate synthase inhibitor in DNA‐repair‐defective human cancer cells

Tatsushi Yokogawa, Wakako Yano, Sayaka Tsukioka,

Cancer Science

2020

38

Discovery of a Novel Class of Potent Human Deoxyuridine Triphosphatase Inhibitors Remarkably Enhancing the Antitumor Activity of Thymidylate Synthase Inhibitors

Seiji Miyahara, Hitoshi Miyakoshi, Tatsushi Yokogawa,

Journal of Medicinal Chemistry

2012

32

TAS-114, a First-in-Class Dual dUTPase/DPD Inhibitor, Demonstrates Potential to Improve Therapeutic Efficacy of Fluoropyrimidine-Based Chemotherapy

Wakako Yano, Tatsushi Yokogawa, Takeshi Wakasa,

Molecular Cancer Therapeutics

2018

29

Discovery of Highly Potent Human Deoxyuridine Triphosphatase Inhibitors Based on the Conformation Restriction Strategy

Seiji Miyahara, Hitoshi Miyakoshi, Tatsushi Yokogawa,

Journal of Medicinal Chemistry

2012

24

Cytotoxicity of trifluridine correlates with the thymidine kinase 1 expression level

Yuki Kataoka, Makoto Iimori, Shinichiro Niimi,

Scientific Reports

2019

21

DNA Replication Stress Induced by Trifluridine Determines Tumor Cell Fate According to p53 Status

Yuki Kataoka, Makoto Iimori, Ryo Fujisawa,

Molecular Cancer Research

2020

17

Synthesis and Discovery of<i>N</i>-Carbonylpyrrolidine- or<i>N</i>-Sulfonylpyrrolidine-Containing Uracil Derivatives as Potent Human Deoxyuridine Triphosphatase Inhibitors

Hitoshi Miyakoshi, Seiji Miyahara, Tatsushi Yokogawa,

Journal of Medicinal Chemistry

2012

15

Thymidine Kinase 1 Loss Confers Trifluridine Resistance without Affecting 5-Fluorouracil Metabolism and Cytotoxicity

Keitaro Edahiro, Makoto Iimori, Takashi Kobunai,

Molecular Cancer Research

2018

13

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