Takeshi Wakasa

Tissue-Restricted Expression of Nrf2 and Its Target Genes in Zebrafish with Gene-Specific Variations in the Induction Profiles

Hitomi Nakajima, Yaeko Nakajima‐Takagi, Tadayuki Tsujita et al. · PLoS ONE · 2011 · 70 citations · Full text

Lipid Peroxidation, Target Genes, Redox Biology +19

1,2,3-Triazole-Containing Uracil Derivatives with Excellent Pharmacokinetics as a Novel Class of Potent Human Deoxyuridine Triphosphatase Inhibitors

Hitoshi Miyakoshi, Seiji Miyahara, Tatsushi Yokogawa et al. · Journal of Medicinal Chemistry · 2012 · 55 citations · Full text

Human Dutpase Inhibitors, Pharmaceutical Science, Pharmacotherapy +19

dUTPase inhibition confers susceptibility to a thymidylate synthase inhibitor in DNA‐repair‐defective human cancer cells

Tatsushi Yokogawa, Wakako Yano, Sayaka Tsukioka et al. · Cancer Science · 2020 · 38 citations · Full text

Tumor Biology, Genome Instability, Dna Damage +10

Discovery of a Novel Class of Potent Human Deoxyuridine Triphosphatase Inhibitors Remarkably Enhancing the Antitumor Activity of Thymidylate Synthase Inhibitors

Seiji Miyahara, Hitoshi Miyakoshi, Tatsushi Yokogawa et al. · Journal of Medicinal Chemistry · 2012 · 32 citations · Full text

Human Dutpase Inhibitors, Antitumor Activity, Chemoprevention Strategy +21

TAS-114, a First-in-Class Dual dUTPase/DPD Inhibitor, Demonstrates Potential to Improve Therapeutic Efficacy of Fluoropyrimidine-Based Chemotherapy

Wakako Yano, Tatsushi Yokogawa, Takeshi Wakasa et al. · Molecular Cancer Therapeutics · 2018 · 29 citations