Concepedia

Hitoshi Miyakoshi

HM

Statistics

Publications

5

Citations

159

H-Index

5

Active since

2012

Affiliations

Taiho Pharmaceutical (Japan)(Current)

Hokkaido University

Gifu Pharmaceutical University

Hitoshi Miyakoshi is an author at Taiho Pharmaceutical (Japan) specializing in enzyme inhibition, chemotherapy, and structure-activity relationships.

Publications per year

2012–2018

5

Publications

5

1,2,3-Triazole-Containing Uracil Derivatives with Excellent Pharmacokinetics as a Novel Class of Potent Human Deoxyuridine Triphosphatase Inhibitors

Hitoshi Miyakoshi, Seiji Miyahara, Tatsushi Yokogawa et al. · Journal of Medicinal Chemistry · 2012 · 56 citations · Full text

, , +9

Discovery of a Novel Class of Potent Human Deoxyuridine Triphosphatase Inhibitors Remarkably Enhancing the Antitumor Activity of Thymidylate Synthase Inhibitors

Seiji Miyahara, Hitoshi Miyakoshi, Tatsushi Yokogawa et al. · Journal of Medicinal Chemistry · 2012 · 33 citations · Full text

, , +11

TAS-114, a First-in-Class Dual dUTPase/DPD Inhibitor, Demonstrates Potential to Improve Therapeutic Efficacy of Fluoropyrimidine-Based Chemotherapy

Wakako Yano, Tatsushi Yokogawa, Takeshi Wakasa et al. · Molecular Cancer Therapeutics · 2018 · 30 citations

, , +15

Discovery of Highly Potent Human Deoxyuridine Triphosphatase Inhibitors Based on the Conformation Restriction Strategy

Seiji Miyahara, Hitoshi Miyakoshi, Tatsushi Yokogawa et al. · Journal of Medicinal Chemistry · 2012 · 25 citations · Full text

, , +10

Synthesis and Discovery of<i>N</i>-Carbonylpyrrolidine- or<i>N</i>-Sulfonylpyrrolidine-Containing Uracil Derivatives as Potent Human Deoxyuridine Triphosphatase Inhibitors

Hitoshi Miyakoshi, Seiji Miyahara, Tatsushi Yokogawa et al. · Journal of Medicinal Chemistry · 2012 · 15 citations · Full text

, , +14

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