Nikolaos Eleftheriadis

Conformational and dynamic plasticity in substrate-binding proteins underlies selective transport in ABC importers

Marijn de Boer, Giorgos Gouridis, Ruslan Vietrov et al. · eLife · 2019 · 142 citations · Full text

Conformational Dynamics, Proteinlipid Interaction, Protein Assembly +17

HDAC1-3 inhibitor MS-275 enhances IL10 expression in RAW264.7 macrophages and reduces cigarette smoke-induced airway inflammation in mice

Niek G.J. Leus, Thea van den Bosch, Petra E. van der Wouden et al. · Scientific Reports · 2017 · 75 citations · Full text

Rational Development of a Potent 15-Lipoxygenase-1 Inhibitor with <i>in Vitro</i> and <i>ex Vivo</i> Anti-inflammatory Properties

Nikolaos Eleftheriadis, Constantinos G. Neochoritis, Niek G.J. Leus et al. · Journal of Medicinal Chemistry · 2015 · 52 citations · Full text

Drug Target, Rational Development, Mammalian Lipoxygenase +18

Design of a novel thiophene inhibitor of 15-lipoxygenase-1 with both anti-inflammatory and neuroprotective properties

Nikolaos Eleftheriadis, Hessel Poelman, Niek G.J. Leus et al. · European Journal of Medicinal Chemistry · 2016 · 48 citations · Full text

Anti-inflammatory, Novel Thiophene Inhibitor, Biochemistry +8

On the impact of competing intra- and intermolecular triplet-state quenching on photobleaching and photoswitching kinetics of organic fluorophores

Jochem H. Smit, Jasper H. M. van der Velde, Jingyi Huang et al. · Physical Chemistry Chemical Physics · 2018 · 42 citations · Full text

Engineering, Molecular Biology, Self-healing Dyes +17