Rocio Zamorano

Selective Actions of Novel Allosteric Modulators Reveal Functional Heteromers of Metabotropic Glutamate Receptors in the CNS

Yin Shen, Meredith J. Noetzel, Kari A. Johnson et al. · Journal of Neuroscience · 2013 · 130 citations · Full text

Synthesis and Evaluation of a Series of Heterobiarylamides That Are Centrally Penetrant Metabotropic Glutamate Receptor 4 (mGluR4) Positive Allosteric Modulators (PAMs)

Darren W. Engers, Colleen M. Niswender, C. David Weaver et al. · Journal of Medicinal Chemistry · 2009 · 81 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Diversity Oriented Synthesis +13

mGlu ₇ potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome

Rocco G. Gogliotti, Rebecca K. Senter, Nicole M. Fisher et al. · Science Translational Medicine · 2017 · 75 citations · Full text

Identification of Positive Allosteric Modulators VU0155094 (ML397) and VU0422288 (ML396) Reveals New Insights into the Biology of Metabotropic Glutamate Receptor 7

Nidhi Jalan‐Sakrikar, Julie R. Field, Rebecca Klar et al. · ACS Chemical Neuroscience · 2014 · 65 citations · Full text

Molecular Biology, New Insights, Mglu7 Activity +17

Discovery, Synthesis, and Structure–Activity Relationship Development of a Series of <i>N</i>-4-(2,5-Dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): Characterization of a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu₄) with Oral Efficacy in an Antiparkinsonian Animal Model

Carrie K. Jones, Darren W. Engers, Analisa D. Thompson et al. · Journal of Medicinal Chemistry · 2011 · 61 citations · Full text

Antiparkinsonian Animal Model, Brain Exposure, Well-established Antiparkinsonian Model +20