Germline Mutations in the Extracellular Domains of the 55 kDa TNF Receptor, TNFR1, Define a Family of Dominantly Inherited Autoinflammatory Syndromes

Michael McDermott, Ivona Aksentijevich, Jérôme Galon, +30

Cell

Molecular PhysiologyAutoimmune DiseaseDisease MechanismDisease EtiologyExtracellular Domains +10

High–monounsaturated fatty acid diets lower both plasma cholesterol and triacylglycerol concentrations

Penny M. Kris‐Etherton, Thomas A. Pearson, Ying Wan, +4

American Journal of Clinical Nutrition

Metabolic SyndromeNutritionOmega-3 Fatty AcidLipid NutritionPhysiology +5

Reduction in Albuminuria Translates to Reduction in Cardiovascular Events in Hypertensive Patients

Hans Ibsen, Michael Hecht Olsen, Kristian Wachtell, +14

Hypertension

Cardiovascular EventsHypertensionUrologyRenal FunctionCardiovascular Epidemiology +13

Effects of cocoa powder and dark chocolate on LDL oxidative susceptibility and prostaglandin concentrations in humans

Ying Wan, Joe A. Vinson, Terry D. Etherton, +3

American Journal of Clinical Nutrition

Food ChemistryNutritionFood Bioactive CompoundMedicineLipid Peroxidation +9

Case-Control Study of the D2 Dopamine Receptor Gene and Smoking Status in Lung Cancer Patients

Margaret R. Spitz, Huihui Shi, Fang Yang, +8

JNCI Journal of the National Cancer Institute

Does albuminuria predict cardiovascular outcome on treatment with losartan versus atenolol in hypertension with left ventricular hypertrophy? A LIFE substudy

Hans Ibsen, Kristian Wachtell, Michael Hecht Olsen, +14

Journal of Hypertension

Thymoquinone attenuates liver fibrosis via PI3K and TLR4 signaling pathways in activated hepatic stellate cells

Ting Bai, Li‐Hua Lian, Yan‐Ling Wu, +2

International Immunopharmacology

Liver FibrosisImmunologyCell DeathPathologyCirrhosis +17

Imetelstat Achieves Meaningful and Durable Transfusion Independence in High Transfusion–Burden Patients With Lower-Risk Myelodysplastic Syndromes in a Phase II Study

David P. Steensma, Pierre Fenaux, Koen Van Eygen, +20

Journal of Clinical Oncology

Imetelstat in patients with lower-risk myelodysplastic syndromes who have relapsed or are refractory to erythropoiesis-stimulating agents (IMerge): a multinational, randomised, double-blind, placebo-controlled, phase 3 trial

Uwe Platzbecker, Valeria Santini, Pierre Fenaux, +21

The Lancet

Hematological MalignancyThrombosisErythropoiesis-stimulating AgentsBone Marrow FailureMalignant Blood Disorder +7

Endoplasmic reticulum stress leads to lipid accumulation through upregulation of SREBP-1c in normal hepatic and hepatoma cells

Dianliang Fang, Ying Wan, Wei Shen, +7

Molecular and Cellular Biochemistry

HepatologyBiochemistryLipid AccumulationNatural SciencesLiver Physiology +11