Germline Mutations in the Extracellular Domains of the 55 kDa TNF Receptor, TNFR1, Define a Family of Dominantly Inherited Autoinflammatory Syndromes

A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease

Stephan R. Targan, Stephen B. Hanauer, Sander J. H. van Deventer et al. · New England Journal of Medicine · 1997 · 3.2K citations · Full text

Pharmacy, Immunology, Inflammation +12

The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation

Hailing Hsu, Jessie Xiong, David V. Goeddel · Cell · 1995 · 2K citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

Klaus Pfeffer, T. Matsuyama, Thomas M. Kündig et al. · Cell · 1993 · 1.7K citations

Life Sciences, Immunology, Infectious Diseases +16

Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis.

Jeanne Keffer, Lesley Probert, Haris Cazlaris et al. · The EMBO Journal · 1991 · 1.7K citations · Full text

Life Sciences, Genetics, Immunology +14

Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)–Fc Fusion Protein

Larry W. Moreland, Scott W. Baumgartner, Michael Schiff et al. · New England Journal of Medicine · 1997 · 1.6K citations · Full text

Life Sciences, Clinical Sciences, Immunology +17