Andrew P. Seddon

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia

David Cunningham, Dennis E. Danley, Kieran F. Geoghegan et al. · Nature Structural & Molecular Biology · 2007 · 434 citations

Familial Hypercholesterolemia, Molecular Physiology, Biochemistry +10

Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules

Xiayang Qiu, Anil Mistry, Mark Ammirati et al. · Nature Structural & Molecular Biology · 2007 · 270 citations

Crystal Structure, Proteinlipid Interaction, Long Tunnel +7

Cloning and Functional Expression of a Human Heparanase Gene

Paul Kussie, Jeffrey D. Hulmes, Dale L. Ludwig et al. · Biochemical and Biophysical Research Communications · 1999 · 200 citations

Medicine, Genetics, Natural Sciences +9

Crystal Structure of the Herpes Simplex Virus 1 DNA Polymerase

Shenping Liu, John D. Knafels, Jeanne S. Chang et al. · Journal of Biological Chemistry · 2006 · 175 citations · Full text

Properly Oriented Heparin−Decasaccharide-Induced Dimers Are the Biologically Active Form of Basic Fibroblast Growth Factor^,

Franklin J. Moy, Michal Safran, Andrew P. Seddon et al. · Biochemistry · 1997 · 95 citations