John D. Knafels

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

Qing‐Jun Meng, Elizabeth S. Maywood, David A. Bechtold et al. · Proceedings of the National Academy of Sciences · 2010 · 255 citations · Full text

Crystal Structure of the Herpes Simplex Virus 1 DNA Polymerase

Shenping Liu, John D. Knafels, Jeanne S. Chang et al. · Journal of Biological Chemistry · 2006 · 175 citations · Full text

Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( <i>S</i> )-2,2-Difluorocyclopropyl)((1 <i>R</i> ,5 <i>S</i> )-3-(2-((1-methyl-1 <i>H</i> -pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)

Andrew Fensome, Catherine M. Ambler, Eric P. Arnold et al. · Journal of Medicinal Chemistry · 2018 · 165 citations · Full text

Complete sequence of the bithorax complex of Drosophila.

Christopher H. Martin, C A Mayeda, C A Davis et al. · Proceedings of the National Academy of Sciences · 1995 · 161 citations · Full text

Biology, Bioinformatics, Medicine +12

Discovery of (<i>S</i>)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1<i>H</i>-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type 2 Diabetes Mellitus

Jeffrey A. Pfefferkorn, Angel Guzmán-Pérez, John Litchfield et al. · Journal of Medicinal Chemistry · 2011 · 114 citations · Full text