Petra Rüger

In Vitro Glycoengineering of IgG1 and Its Effect on Fc Receptor Binding and ADCC Activity

Marco Thomann, Tilman Schlothauer, Tetyana Dashivets et al. · PLoS ONE · 2015 · 213 citations · Full text

Glycobiology, Immunology, Vitro Glycoengineering +23

Delivery of the Brainshuttle™ amyloid-beta antibody fusion trontinemab to non-human primate brain and projected efficacious dose regimens in humans

Hans Peter Grimm, Vanessa Schumacher, Martin Schäfer et al. · mAbs · 2023 · 133 citations · Full text

A Pentacyclic Aurora Kinase Inhibitor (AKI-001) with High in Vivo Potency and Oral Bioavailability

Thomas E. Rawson, Matthias Rüth, Elizabeth Blackwood et al. · Journal of Medicinal Chemistry · 2008 · 58 citations · Full text

Medicinal Chemistry, Oral Bioavailability, Novel Therapy +14

Mutants of Protein Kinase A that Mimic the ATP-binding Site of Protein Kinase B (AKT)

M. Gaßel, C.B. Breitenlechner, Petra Rüger et al. · Journal of Molecular Biology · 2003 · 54 citations

Protein Kinase A, Signal Transduction, Molecular Physiology +11

Development of a pre-glycoengineered CHO-K1 host cell line for the expression of antibodies with enhanced Fc mediated effector function

Oliver Popp, Samuel Moser, Jörg Zielonka et al. · mAbs · 2017 · 28 citations · Full text