C.B. Breitenlechner

Protein Kinase A in Complex with Rho-Kinase Inhibitors Y-27632, Fasudil, and H-1152P

C.B. Breitenlechner, M. Gaßel, Hiroyoshi Hidaka et al. · Structure · 2003 · 158 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Structure-Based Optimization of Novel Azepane Derivatives as PKB Inhibitors

C.B. Breitenlechner, Thomas Wegge, L. Berillon et al. · Journal of Medicinal Chemistry · 2004 · 101 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Crystal Structures of Active Src Kinase Domain Complexes

C.B. Breitenlechner, Norman Kairies, Konrad Honold et al. · Journal of Molecular Biology · 2005 · 76 citations

Life Sciences, Biochemistry, Molecular Biology +14

Design and Crystal Structures of Protein Kinase B-Selective Inhibitors in Complex with Protein Kinase A and Mutants

C.B. Breitenlechner, Walter-Gunar Friebe, Emmanuel Brunet et al. · Journal of Medicinal Chemistry · 2004 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Mutants of Protein Kinase A that Mimic the ATP-binding Site of Protein Kinase B (AKT)

M. Gaßel, C.B. Breitenlechner, Petra Rüger et al. · Journal of Molecular Biology · 2003 · 54 citations

Life Sciences, Biochemistry, Molecular Biology +13