Thomas Wegge

Structure-Based Optimization of Novel Azepane Derivatives as PKB Inhibitors

C.B. Breitenlechner, Thomas Wegge, L. Berillon et al. · Journal of Medicinal Chemistry · 2004 · 101 citations · Full text

Synthesis and Nicotinic Binding Studies on Enantiopure Diazine Analogues of the Novel (2-Chloro-5-pyridyl)-9-azabicyclo[4.2.1]non-2-ene UB-165

Holger Gohlke, Daniela Gündisch, Simone Schwarz et al. · Journal of Medicinal Chemistry · 2002 · 60 citations · Full text

Combinatorial Chemistry, Bioorganic Chemistry, Binding Affinity +16

<i>exo</i>-2-(Pyridazin-4-yl)-7-azabicyclo[2.2.1]heptanes:  Syntheses and Nicotinic Acetylcholine Receptor Agonist Activity of Potent Pyridazine Analogues of (±)-Epibatidine

Daqing Che, Thomas Wegge, Milton T. Stubbs et al. · Journal of Medicinal Chemistry · 2000 · 51 citations

Combinatorial Chemistry, Bioorganic Chemistry, Organic Chemistry +20

Syntheses and evaluation of pyridazine and pyrimidine Containing bioisosteres of (±)-Pyrido[3.4-b]homotropane and Pyrido-[3.4-b]tropane as novel nAChR ligands

Daniela Gündisch, Thomas Kämpchen, Simone Schwarz et al. · Bioorganic & Medicinal Chemistry · 2002 · 48 citations

Bioorganic Chemistry, Natural Sciences, Medicine +8

3D QSAR Analyses-Guided Rational Design of Novel Ligands for the (α4)₂(β2)₃ Nicotinic Acetylcholine Receptor

Holger Gohlke, Simone Schwarz, Daniela Gündisch et al. · Journal of Medicinal Chemistry · 2003 · 44 citations · Full text