M.G. Gruetter

Structural Modification of the P2‘ Position of 2,7-Dialkyl-Substituted 5( <i>S</i> )-Amino-4( <i>S</i> )-hydroxy-8-phenyl-octanecarboxamides:  The Discovery of Aliskiren, a Potent Nonpeptide Human Renin Inhibitor Active after Once Daily Dosing in Marmosets

Jürgen Maibaum, Stefan Stutz, Richard Göschke et al. · Journal of Medicinal Chemistry · 2007 · 95 citations · Full text

Structural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide Receptor

Peter Ravn, Chaithanya Madhurantakam, Susan Kunze et al. · Journal of Biological Chemistry · 2013 · 83 citations · Full text

Novel 2,7-Dialkyl-Substituted 5(<i>S</i>)-Amino-4(<i>S</i>)-hydroxy-8-phenyl-octanecarboxamide Transition State Peptidomimetics Are Potent and Orally Active Inhibitors of Human Renin

Richard Göschke, Stefan Stutz, Vittorio Rasetti et al. · Journal of Medicinal Chemistry · 2007 · 49 citations · Full text

Hypertension, Novel 2,7-Dialkyl-substituted 5, Pharmacotherapy +17

Changing the inhibitory specificity and function of the proteinase inhibitor eglin c by site-directed mutagenesis: functional and structural investigation

Dirk W. Heinz, Sven G. Hyberts, John P. Priestle et al. · Biochemistry · 1992 · 41 citations

High-resolution structure of the temperature-sensitive mutant of phage lysozyme, Arg 96 .fwdarw. His

L.H. Weaver, Terry M. Gray, M.G. Gruetter et al. · Biochemistry · 1989 · 39 citations