Susan R. Rippin

Birinapant (TL32711), a Bivalent SMAC Mimetic, Targets TRAF2-Associated cIAPs, Abrogates TNF-Induced NF-κB Activation, and Is Active in Patient-Derived Xenograft Models

Christopher A. Benetatos, Yasuhiro Mitsuuchi, Jennifer M. Burns et al. · Molecular Cancer Therapeutics · 2014 · 175 citations

Life Sciences, Oncology, Pharmacology +17

Birinapant, a Smac-Mimetic with Improved Tolerability for the Treatment of Solid Tumors and Hematological Malignancies

Stephen M. Condon, Yasuhiro Mitsuuchi, Yijun Deng et al. · Journal of Medicinal Chemistry · 2014 · 151 citations

Medicine, Oncology, Pharmacology +13

<i>N</i>-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1<i>H</i>)-yl)carboxamides:  Identification of Novel Orthopoxvirus Egress Inhibitors

T. R. Bailey, Susan R. Rippin, Elizabeth Opsitnick et al. · Journal of Medicinal Chemistry · 2007 · 65 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

The Discovery of Pyrano[3,4‐<i>b</i>]indole‐Based Allosteric Inhibitors of HCV NS5B Polymerase with In Vivo Activity

Matthew G. LaPorte, Randy W. Jackson, Tandy L. Draper et al. · ChemMedChem · 2008 · 29 citations

Medicine, Infectious Diseases, Medicinal Chemistry +15

The discovery and structure–activity relationships of pyrano[3,4-b]indole-based inhibitors of hepatitis C virus NS5B polymerase

Randy W. Jackson, Matthew G. LaPorte, Torsten Herbertz et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 23 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14