Jack Houston

Circular ecDNA promotes accessible chromatin and high oncogene expression

Sihan Wu, Kristen M. Turner, Nam Nguyen et al. · Nature · 2019 · 659 citations · Full text

Chromatin, Dna, Chromatin Structure +10

A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase

Mary E. Matyskiela, Gang Lu, Takumi Ito et al. · Nature · 2016 · 628 citations

Protein Function, Signal Transduction, Cell Regulation +10

EGFR is required for Wnt9a–Fzd9b signalling specificity in haematopoietic stem cells

Stephanie Grainger, Nicole Nguyen, Jenna Richter et al. · Nature Cell Biology · 2019 · 63 citations

Tissue Development, Developmental Biology, Haematopoietic Stem Cells +7

BUB-1 and CENP-C recruit PLK-1 to control chromosome alignment and segregation during meiosis I in C. elegans oocytes

Samuel J.P. Taylor, Laura Bel Borja, Flavie Soubigou et al. · eLife · 2023 · 23 citations · Full text

CC-92480, a Novel Cereblon E3 Ligase Modulator, Is Synergistic with Dexamethasone, Bortezomib, and Daratumumab in Multiple Myeloma

Lilly Wong, Rama Krishna Narla, Jim Leisten et al. · Blood · 2019 · 18 citations