Zachary D. Nagel

ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade

Jianfeng Shen, Zhenlin Ju, Zhao Wei et al. · Nature Medicine · 2018 · 571 citations

Medicine, Immunology, Oncology +16

WRN helicase is a synthetic lethal target in microsatellite unstable cancers

Edmond M. Chan, Tsukasa Shibue, James M. McFarland et al. · Nature · 2019 · 472 citations · Full text

Life Sciences, Molecular Biology, Oncology +11

Adaptive mutability of colorectal cancers in response to targeted therapies

Mariangela Russo, Giovanni Crisafulli, Alberto Sogari et al. · Science · 2019 · 446 citations · Full text

Medicine, Cancer Biology, Oncology +17

A 21st century revisionist's view at a turning point in enzymology

Zachary D. Nagel, Judith P. Klinman · Nature Chemical Biology · 2009 · 289 citations

Life Sciences, Biology, Enzymology +5

Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis

Zachary D. Nagel, Carrie M. Margulies, Isaac A. Chaim et al. · Proceedings of the National Academy of Sciences · 2014 · 168 citations · Full text

Life Sciences, Genetics, Molecular Biology +16