Carrie M. Margulies

Characterization of the interplay between DNA repair and CRISPR/Cas9-induced DNA lesions at an endogenous locus

Anne Bothmer, Tanushree Phadke, Luis Barrera et al. · Nature Communications · 2017 · 194 citations · Full text

Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis

Zachary D. Nagel, Carrie M. Margulies, Isaac A. Chaim et al. · Proceedings of the National Academy of Sciences · 2014 · 167 citations · Full text

A highly efficient transgene knock-in technology in clinically relevant cell types

Alexander G. Allen, Samia Khan, Carrie M. Margulies et al. · Nature Biotechnology · 2023 · 56 citations

Regenerative Medicine, Relevant Cell Types, Cell Therapy +10

Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper‐IgM syndrome

Valentina Vavassori, E. Mercuri, Genni Enza Marcovecchio et al. · EMBO Molecular Medicine · 2021 · 49 citations · Full text

ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage

Jennifer Jordan, Sophea Chhim, Carrie M. Margulies et al. · Cell Death and Disease · 2017 · 15 citations · Full text

Apoptosis, Immunology, Pathology +19