Trenton T. Ross

ACC inhibitor alone or co-administered with a DGAT2 inhibitor in patients with non-alcoholic fatty liver disease: two parallel, placebo-controlled, randomized phase 2a trials

Roberto A. Calle, Neeta B. Amin, Santos Carvajal‐Gonzalez et al. · Nature Medicine · 2021 · 207 citations

Obesity, Metabolic Syndrome, Dgat2 Inhibitor +12

An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD)

Michèle Vacca, Ioannis Kamzolas, Lea Mørch Harder et al. · Nature Metabolism · 2024 · 183 citations · Full text

Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems

Trenton T. Ross, Collin Crowley, Kenneth L. Kelly et al. · Cellular and Molecular Gastroenterology and Hepatology · 2020 · 89 citations · Full text

Pharmacologic inhibition of ketohexokinase prevents fructose-induced metabolic dysfunction

Jemy A. Gutierrez, Wei Liu, Sylvie Perez et al. · Molecular Metabolism · 2021 · 80 citations · Full text

Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK)

Kim Huard, Kay Ahn, Paul A. Amor et al. · Journal of Medicinal Chemistry · 2017 · 49 citations · Full text

Metabolic Syndrome, Medicinal Chemistry, Vivo Inhibition +14