Chrysa Malosh

Chemical inhibition of fatty acid absorption and cellular uptake limits lipotoxic cell death

Constance Ahowesso, Paul N. Black, Nipun Saini et al. · Biochemical Pharmacology · 2015 · 62 citations

Life Sciences, Biochemistry, Toxicology +12

mGlu₅positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome

Rocco G. Gogliotti, Rebecca K. Senter, Jerri M. Rook et al. · Human Molecular Genetics · 2016 · 60 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Identification of Specific Ligand–Receptor Interactions That Govern Binding and Cooperativity of Diverse Modulators to a Common Metabotropic Glutamate Receptor 5 Allosteric Site

Karen J. Gregory, Elizabeth D. Nguyen, Chrysa Malosh et al. · ACS Chemical Neuroscience · 2014 · 48 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Tetrahydronaphthyridine and Dihydronaphthyridinone Ethers As Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 5 (mGlu₅)

Mark Turlington, Chrysa Malosh, Jon Jacobs et al. · Journal of Medicinal Chemistry · 2014 · 13 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14