Elizabeth D. Nguyen

Small-molecule ligand docking into comparative models with Rosetta

Steven A. Combs, Samuel DeLuca, Stephanie H. DeLuca et al. · Nature Protocols · 2013 · 191 citations

Pharmacy, Chemistry, Medicinal Chemistry +13

Probing the Metabotropic Glutamate Receptor 5 (mGlu5) Positive Allosteric Modulator (PAM) Binding Pocket: Discovery of Point Mutations That Engender a “Molecular Switch” in PAM Pharmacology

Karen J. Gregory, Elizabeth D. Nguyen, Sean D. Reiff et al. · Molecular Pharmacology · 2013 · 73 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Adenovirus-Mediated <i>XIAP</i> Gene Transfer Reverses the Negative Effects of Immunosuppressive Drugs on Insulin Secretion and Cell Viability of Isolated Human Islets

Hongxiang Hui, Nasif Khoury, Xiaoning Zhao et al. · Diabetes · 2005 · 65 citations

Medicine, Endocrinology, Pharmacology +17

Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis

Daryl M. Okamura, Chris M. Brewer, Paul Wakenight et al. · iScience · 2021 · 50 citations · Full text

Medicine, Molecular Biology, Nephrology +17

Identification of Specific Ligand–Receptor Interactions That Govern Binding and Cooperativity of Diverse Modulators to a Common Metabotropic Glutamate Receptor 5 Allosteric Site

Karen J. Gregory, Elizabeth D. Nguyen, Chrysa Malosh et al. · ACS Chemical Neuroscience · 2014 · 48 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17