Karl Dean

<i>N</i>-Hydroxy-3-phenyl-2-propenamides as Novel Inhibitors of Human Histone Deacetylase with in Vivo Antitumor Activity:  Discovery of (2<i>E</i>)-<i>N</i>-Hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1<i>H</i>-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824)

Stacy Remiszewski, Lidia Sambucetti, Kenneth W. Bair et al. · Journal of Medicinal Chemistry · 2003 · 129 citations · Full text

Medicine, Oncology, Pharmacology +13

Role of the AcrAB-TolC Efflux Pump in Determining Susceptibility of <i>Haemophilus influenzae</i> to the Novel Peptide Deformylase Inhibitor LBM415

Charles R. Dean, Shubha Narayan, Denis M. Daigle et al. · Antimicrobial Agents and Chemotherapy · 2005 · 47 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +12

A Practical Enantioselective Synthesis of a Novel Peptide Deformylase Inhibitor

Joel Slade, David Parker, Michael Girgis et al. · Organic Process Research & Development · 2005 · 24 citations

Pharmacy, Biochemistry, Medicinal Chemistry +13

Biophysical Investigation of the Mode of Inhibition of Tetramic Acids, the Allosteric Inhibitors of Undecaprenyl Pyrophosphate Synthase

Lac V. Lee, Brian Granda, Karl Dean et al. · Biochemistry · 2010 · 19 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Antibacterial and Solubility Optimization of Thiomuracin A

Matthew J. LaMarche, Jennifer A. Leeds, J.T. Brewer et al. · Journal of Medicinal Chemistry · 2016 · 14 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17