Shuaige Wang

Discovery of 1-[3-(Aminomethyl)phenyl]-<i>N</i>-[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1<i>H</i>-pyrazole-5-carboxamide (DPC423), a Highly Potent, Selective, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa

Donald Pinto, Michael J. Orwat, Shuaige Wang et al. · Journal of Medicinal Chemistry · 2001 · 172 citations · Full text

Medicine, Pharmacology, Drug Discovery +11

Discovery of Potent Isoxazoline Glycoprotein IIb/IIIa Receptor Antagonists

John Wityak, Thais M. Sielecki, Donald Pinto et al. · Journal of Medicinal Chemistry · 1997 · 72 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Discovery of an Orally Active Series of Isoxazoline Glycoprotein IIb/IIIa Antagonists

Chu‐Biao Xue, John Wityak, Thais M. Sielecki et al. · Journal of Medicinal Chemistry · 1997 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

SAR and factor IXa crystal structure of a dual inhibitor of factors IXa and Xa

Joanne M. Smallheer, Richard Alexander, Jianmin Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 41 citations · Full text

Natural Sciences, Medicinal Chemistry, Pharmacology +16

Synthesis and SAR of benzamidine factor Xa inhibitors containing a vicinally-substituted heterocyclic core

John M. Fevig, Donald Pinto, Qi Han et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12