Concepedia

Synthesis and SAR of benzamidine factor Xa inhibitors containing a vicinally-substituted heterocyclic core

John M. Fevig, Donald Pinto, Qi Han, Mimi L. Quan, James R. Pruitt, Irina C. Jacobson, Robert A. Galemmo, Shuaige Wang, Michael J. Orwat, Lori L. Bostrom,

Bioorganic & Medicinal Chemistry Letters · 2001 · 40 citations · 9 references

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References

9

A mild, general method for conversion of esters to amides

Anwer Basha, Michael F. Lipton, Steven M. Weinreb · Tetrahedron Letters · 1977 · 560 citations

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The selective inhibition of thrombin by peptides of boroarginine.

Charles A. Kettner, Lawrence J. Mersinger, Robert M. Knabb · Journal of Biological Chemistry · 1990 · 253 citations · Full text

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Discovery of 1-[3-(Aminomethyl)phenyl]-<i>N</i>-[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1<i>H</i>-pyrazole-5-carboxamide (DPC423), a Highly Potent, Selective, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa

Donald Pinto, Michael J. Orwat, Shuaige Wang et al. · Journal of Medicinal Chemistry · 2001 · 172 citations · Full text

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Synthesis of NF-κB activation inhibitors derived from epoxyquinomicin C

Naoki Matsumoto, Akiko Ariga, Sakino To‐e et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 161 citations

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Design and Synthesis of Isoxazoline Derivatives as Factor Xa Inhibitors. 1

Mimi L. Quan, Ann Y. Liauw, Christopher D. Ellis et al. · Journal of Medicinal Chemistry · 1999 · 80 citations · Full text

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