Lori L. Bostrom

Structure-Based Design and Discovery of Protein Tyrosine Phosphatase Inhibitors Incorporating Novel Isothiazolidinone Heterocyclic Phosphotyrosine Mimetics

Andrew P. Combs, Eddy W. Yue, Michael J. Bower et al. · Journal of Medicinal Chemistry · 2005 · 101 citations · Full text

Molecular Docking, Crystal Structure, Medicinal Chemistry +13

Design and Synthesis of Isoxazoline Derivatives as Factor Xa Inhibitors. 1

Mimi L. Quan, Ann Y. Liauw, Christopher D. Ellis et al. · Journal of Medicinal Chemistry · 1999 · 80 citations · Full text

Discovery of 1-(2-Aminomethylphenyl)-3-trifluoromethyl-<i>N</i>- [3-fluoro-2‘-(aminosulfonyl)[1,1‘-biphenyl)]-4-yl]-1<i>H</i>-pyrazole-5-carboxyamide (DPC602), a Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor

James R. Pruitt, Donald Pinto, Robert A. Galemmo et al. · Journal of Medicinal Chemistry · 2003 · 75 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Chemical Biology +18

Isoxazolines and isoxazoles as factor Xa inhibitors

James R. Pruitt, Donald Pinto, Melissa Estrella et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 67 citations · Full text

Medicinal Chemistry, Medicine, Mechanism Of Action +6

Discovery of an Orally Active Series of Isoxazoline Glycoprotein IIb/IIIa Antagonists

Chu‐Biao Xue, John Wityak, Thais M. Sielecki et al. · Journal of Medicinal Chemistry · 1997 · 64 citations · Full text

Pharmaceutical Science, Orally Active Series, Glycobiology +17