Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence

Julian Schulze zur Wiesch, Donatella Ciuffreda, Lia Laura Lewis‐Ximenez, +12

The Journal of Experimental Medicine

Fc Glycan-Mediated Regulation of Placental Antibody Transfer

Madeleine F. Jennewein, Ilona T. Goldfarb, Sepideh Dolatshahi, +20

Cell

Maternal ImmunizationImmunologyPlacental Antibody TransferAntibody EngineeringImmunotherapy +4

Phenotype and function of HBV-specific T cells is determined by the targeted epitope in addition to the stage of infection

Ruben C. Hoogeveen, Maxwell Robidoux, Tatjana Schwarz, +14

Gut

Differentiation of exhausted CD8+ T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory

Pierre Tonnerre, David Wolski, Sonu Subudhi, +27

Nature Immunology

Autoimmune DiseaseAdaptive Immune SystemT-regulatory CellImmunologyChronic Antigen Stimulation +8

Liver Environment and HCV Replication Affect Human T-Cell Phenotype and Expression of Inhibitory Receptors

Daniela C. Kroy, Donatella Ciuffreda, Jennifer H. Cooperrider, +15

Gastroenterology

Hepatic DisordersAutoimmune DiseaseHepatologyLiver EnvironmentViral Hepatitis +10

Early Transcriptional Divergence Marks Virus-Specific Primary Human CD8+ T Cells in Chronic versus Acute Infection

David Wolski, Peter K. Foote, Diana Y. Chen, +17

Immunity

Viral PersistenceHuman RetrovirusPathogenesisImmunologyAntiviral Response +5

Hepatitis C virus–specific CD4+ T cell phenotype and function in different infection outcomes

Diana Y. Chen, David Wolski, Jasneet Aneja, +10

Journal of Clinical Investigation

Adaptive Immune SystemImmunologyCd4 T Cell ResponsesViral HepatitisHuman Retrovirus +14

Hepatitis B virus-specific CD4 T cell responses differentiate functional cure from chronic surface antigen+ infection

Ruben C. Hoogeveen, Suzan Dijkstra, Lea M. Bartsch, +14

Journal of Hepatology

Autoimmune DiseaseViral HepatitisImmunologyHepatitis BHepatitis +7

Single-cell atlas of the liver myeloid compartment before and after cure of chronic viral hepatitis

Ang Cui, Bo Li, Michael S. Wallace, +28

Journal of Hepatology

Single-cell AtlasChronic Viral HepatitisHepatologyViral HepatitisLiver Physiology +11

Underascertainment of Acute Hepatitis C Virus Infections in the U.S. Surveillance System

Shauna Onofrey, Jasneet Aneja, Gillian Haney, +11

Annals of Internal Medicine