CD39 Expression Identifies Terminally Exhausted CD8+ T Cells

Prakash Gupta, Jernej Godec, David Wolski, +14

PLoS Pathogens

Human RetrovirusTerminal ExhaustionViral ImmunityImmunologyAntiviral Response +11

Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans

Kathleen B. Yates, Pierre Tonnerre, Geneviève Martin, +15

Nature Immunology

Epigenetic ScarsAutoimmune DiseaseT-regulatory CellImmunologyPathology +9

Kinetic differences in the induction of interferon stimulated genes by interferon-α and interleukin 28B are altered by infection with hepatitis C virus

Nikolaus Jilg, Wenyu Lin, Jian Hong, +14

Hepatology

Differentiation of exhausted CD8+ T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory

Pierre Tonnerre, David Wolski, Sonu Subudhi, +27

Nature Immunology

Autoimmune DiseaseAdaptive Immune SystemT-regulatory CellImmunologyChronic Antigen Stimulation +8

Liver Environment and HCV Replication Affect Human T-Cell Phenotype and Expression of Inhibitory Receptors

Daniela C. Kroy, Donatella Ciuffreda, Jennifer H. Cooperrider, +15

Gastroenterology

Hepatic DisordersAutoimmune DiseaseHepatologyLiver EnvironmentViral Hepatitis +10

Bystander Chronic Infection Negatively Impacts Development of CD8+ T Cell Memory

Erietta Stelekati, Haina Shin, Travis A. Doering, +13

Immunity

Autoimmune DiseaseT-regulatory CellImmunologyBystander Chronic InfectionAutoimmunity +4

Early Transcriptional Divergence Marks Virus-Specific Primary Human CD8+ T Cells in Chronic versus Acute Infection

David Wolski, Peter K. Foote, Diana Y. Chen, +17

Immunity

Viral PersistenceHuman RetrovirusPathogenesisImmunologyAntiviral Response +5

Hepatitis C virus–specific CD4+ T cell phenotype and function in different infection outcomes

Diana Y. Chen, David Wolski, Jasneet Aneja, +10

Journal of Clinical Investigation

Adaptive Immune SystemImmunologyCd4 T Cell ResponsesViral HepatitisHuman Retrovirus +14

Evolution of the innate and adaptive immune response in women with acute Zika virus infection

Pierre Tonnerre, Juliana Gil Melgaço, Almudena Torres-Cornejo, +15

Nature Microbiology

VaccinationHost ResponseAdaptive Immune ResponseInnate Immune SystemImmunology +6

Differentiation of exhausted CD8 T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory

Pierre Tonnerre, David Wolski, Sonu Subudhi, +27