Eugene C. Petrella

High-Density Miniaturized Thermal Shift Assays as a General Strategy for Drug Discovery

Michael W. Pantoliano, Eugene C. Petrella, Joseph D. Kwasnoski et al. · SLAS DISCOVERY · 2001 · 877 citations · Full text

Pharmaceutical Research, General Strategy, Engineering +11

Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells

Bruce Grasberger, Tianbao Lu, Carsten J. Schubert et al. · Journal of Medicinal Chemistry · 2005 · 425 citations · Full text

Molecular Biology, Chemical Biology, Pharmaceutical Chemistry +20

Natural products reveal cancer cell dependence on oxysterol-binding proteins

Anthony W. G. Burgett, Thomas B. Poulsen, Kittikhun Wangkanont et al. · Nature Chemical Biology · 2011 · 255 citations · Full text

Biochemistry, Oncogenic Agent, Medicine +5

Phospholipid/Alkanethiol Bilayers for Cell-Surface Receptor Studies by Surface Plasmon Resonance

Anne L. Plant, Michael Brigham‐Burke, Eugene C. Petrella et al. · Analytical Biochemistry · 1995 · 186 citations · Full text

Proteinlipid Interaction, Engineering, Biochemistry +11

1,4-Benzodiazepine-2,5-diones as small molecule antagonists of the HDM2–p53 interaction: discovery and SAR

Daniel J. Parks, Louis V. LaFrance, Raul R. Calvo et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 166 citations

Molecular Pharmacology, Drug Target, Small Molecule Antagonists +11