Michael W. Pantoliano

High-Density Miniaturized Thermal Shift Assays as a General Strategy for Drug Discovery

Michael W. Pantoliano, Eugene C. Petrella, Joseph D. Kwasnoski et al. · SLAS DISCOVERY · 2001 · 877 citations · Full text

Pharmaceutical Research, General Strategy, Engineering +11

ACE2 X-Ray Structures Reveal a Large Hinge-bending Motion Important for Inhibitor Binding and Catalysis

Paul Towler, Bart L. Staker, Sridhar G. Prasad et al. · Journal of Biological Chemistry · 2004 · 738 citations · Full text

X-ray Crystallography, Engineering, Biochemistry +9

Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells

Bruce Grasberger, Tianbao Lu, Carsten J. Schubert et al. · Journal of Medicinal Chemistry · 2005 · 425 citations · Full text

Molecular Biology, Chemical Biology, Pharmaceutical Chemistry +20

In Vivo Tumor Targeting of a Recombinant Single-Chain Antigen-Binding Protein

David Colcher, Robert E. Bird, Mario Roselli et al. · JNCI Journal of the National Cancer Institute · 1990 · 303 citations

Immunocytochemical Technique, Vivo Targeting, Immunology +19

Energetic Characterization of the Basic Fibroblast Growth Factor-Heparin Interaction: Identification of the Heparin Binding Domain

L D Thompson, Michael W. Pantoliano, Barry A. Springer · Biochemistry · 1994 · 297 citations