Holger M. Becker

Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy

Kathrin Renner, Annette Schnell, Gudrun E. Koehl et al. · Cell Reports · 2019 · 298 citations · Full text

Medicine, Cancer Biology, Immunology +17

Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects

Cyril Corbet, Estelle Bastien, Nihed Draoui et al. · Nature Communications · 2018 · 188 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function

Somayeh Jamali, Michael Klier, Samantha Ames et al. · Scientific Reports · 2015 · 129 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Branched‐chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype

Lidia Santos Silva, Gernot Poschet, Yannic Nonnenmacher et al. · EMBO Reports · 2017 · 106 citations · Full text

Medicine, Cancer Biology, Oncology +14

Transport Activity of MCT1 Expressed in Xenopus Oocytes Is Increased by Interaction with Carbonic Anhydrase

Holger M. Becker, Daniela Hirnet, Claudia Fecher‐Trost et al. · Journal of Biological Chemistry · 2005 · 101 citations · Full text

Life Sciences, Biochemistry, Physiology +17