Gernot Poschet

IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression

Ahmed Sadik, Luis F. Somarribas Patterson, Selcen Öztürk et al. · Cell · 2020 · 540 citations · Full text

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate

Lukas Bunse, Stefan Pusch, Theresa Bunse et al. · Nature Medicine · 2018 · 515 citations

Cancer Immunosurveillance, Medicine, T-regulatory Cell +9

BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation

Simon Raffel, Mattia Falcone, Niclas Kneisel et al. · Nature · 2017 · 341 citations

Idhmut-like Dna Hypermethylation, Chromatin, Transcriptional Regulation +14

Proton‐driven sucrose symport and antiport are provided by the vacuolar transporters SUC4 and TMT1/2

Alexander Schulz, Diana Beyhl, Irene Marten et al. · The Plant Journal · 2011 · 255 citations

Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas

Mirco Friedrich, Roman Sankowski, Lukas Bunse et al. · Nature Cancer · 2021 · 216 citations · Full text