Mattia Falcone

Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion

Anna Paczulla, Kathrin Rothfelder, Simon Raffel et al. · Nature · 2019 · 367 citations · Full text

Immune Evasion, Cell Therapy, Medicine +5

BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation

Simon Raffel, Mattia Falcone, Niclas Kneisel et al. · Nature · 2017 · 341 citations

Idhmut-like Dna Hypermethylation, Chromatin, Transcriptional Regulation +14

Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma

Chiara Ambrogio, Gonzalo Goméz-López, Mattia Falcone et al. · Nature Medicine · 2016 · 179 citations · Full text

Tumor Biology, Medicine, Therapeutic Strategy +11

Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin

Elisa Espinet, Zuguang Gu, Charles D. Imbusch et al. · Cancer Discovery · 2020 · 126 citations · Full text

Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells

Alice C. Newman, Mattia Falcone, Alejandro Huerta Uribe et al. · Molecular Cell · 2021 · 103 citations · Full text

Cancer Research, Pancreatic Cancer, One-carbon Units +15