Alejandro Huerta Uribe

Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells

Alice C. Newman, Mattia Falcone, Alejandro Huerta Uribe et al. · Molecular Cell · 2021 · 112 citations · Full text

Life Sciences, Biochemistry, Oncology +17

SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis

Erica Pranzini, Elisa Pardella, Livio Muccillo et al. · Cell Reports · 2022 · 96 citations · Full text

Medicine, Oncology, Pharmacology +17

Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma

Mahnoor Mahmood, Eric Minwei Liu, Amy L. Shergold et al. · Nature Cancer · 2024 · 85 citations · Full text

Medicine, Cancer Biology, Oncology +17

Polyamine pathway activity promotes cysteine essentiality in cancer cells

Tong Zhang, Christin Bauer, Alice C. Newman et al. · Nature Metabolism · 2020 · 60 citations

Medicine, Cancer Biology, Molecular Biology +14

Sensitisation of cancer cells to radiotherapy by serine and glycine starvation

Mattia Falcone, Alejandro Huerta Uribe, Alice C. Newman et al. · British Journal of Cancer · 2022 · 59 citations · Full text

Medicine, Cancer Biology, Oncology +17