Stephen A. Fakhoury

Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor

Andrea J. Gonzales, Kenneth E. Hook, Irene W. Althaus et al. · Molecular Cancer Therapeutics · 2008 · 221 citations · Full text

Medicine, Oncology, Pharmacology +15

Inhibition of human immunodeficiency virus 1 protease in vitro: rational design of substrate analogue inhibitors.

Geoffrey B. Dreyer, Brian W. Metcalf, Thaddeus A. Tomaszek et al. · Proceedings of the National Academy of Sciences · 1989 · 202 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

Peptide substrates and inhibitors of the HIV-1 protease

Michael L. Moore, William M. Bryan, Stephen A. Fakhoury et al. · Biochemical and Biophysical Research Communications · 1989 · 161 citations

Life Sciences, Biochemistry, Molecular Biology +14

Human immunodeficiency virus-1 protease. 1. Initial velocity studies and kinetic characterization of reaction intermediates by oxygen-18 isotope exchange

Lawrence J. Hyland, Thaddeus A. Tomaszek, Gerald D. Roberts et al. · Biochemistry · 1991 · 114 citations

Life Sciences, Biochemistry, Chemistry +13

Pyridone-Containing farnesyltransferase inhibitors: synthesis and biological evaluation

Lisa Hasvold, Weibo Wang, Stephen L. Gwaltney et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 74 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10