Thaddeus A. Tomaszek

Author

New Frontier

Also Known As

T A Tomaszek, T. A. JUN. TOMASZEK, T. A. Tomaszek, T. Tomaszek, Thaddeus A. Tomaszek, Thaddeus Tomaszek, Tomaszek, T.

Publications

3.4K

Citations

H-Index

Concepts

All Affiliations

New Frontier GlaxoSmithKline (United States)South College GlaxoSmithKline (United Kingdom)University of Nebraska–Lincoln

About

Thaddeus A. Tomaszek is an author at New Frontier specializing in medicine, biochemistry, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	22	27	2K
2	Biochemistry	20	23	1.6K
3	Natural Sciences	18	21	1.5K
4	Health Sciences	3	3	182
5	Biomolecular Engineering	1	1	38

Thaddeus A. Tomaszek

Publications

3.4K

Citations

H-Index

Page 1

	Year	Citations
Proteolytic Activity of Human Osteoclast Cathepsin K Mary J. Bossard, Thaddeus A. Tomaszek, Scott K. Thompson, Journal of Biological Chemistry	1996	488
Human immunodeficiency virus-1 protease. 2. Use of pH rate studies and solvent kinetic isotope effects to elucidate details of chemical mechanism Lawrence J. Hyland, Thaddeus A. Tomaszek, Thomas D. Meek Biochemistry	1991	245
Potent and Selective Nonpeptide Inhibitors of Caspases 3 and 7 Inhibit Apoptosis and Maintain Cell Functionality Dennis Lee, Scott A. Long, Jerry L. Adams, Journal of Biological Chemistry	2000	232
Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues Thomas D. Meek, Dennis M. Lambert, Geoffrey B. Dreyer, Nature Hiv-1 ProteaseBiochemistryHuman RetrovirusImmunologyAntiviral Response	1990	231
Inhibition of human immunodeficiency virus 1 protease in vitro: rational design of substrate analogue inhibitors. Geoffrey B. Dreyer, Brian W. Metcalf, Thaddeus A. Tomaszek, Proceedings of the National Academy of Sciences Substrate Analogue InhibitorsPeptide AnaloguesImmunologyAntiviral DrugMedicinal Chemistry	1989	202
4-Aryl-1,2,3-triazole: A Novel Template for a Reversible Methionine Aminopeptidase 2 Inhibitor, Optimized To Inhibit Angiogenesis in Vivo Lara S. Kallander, Qing Lü, Wenfang Chen, Journal of Medicinal Chemistry Mouse Matrigel ModelEndothelial Cell GrowthPharmacotherapyChemical BiologyPharmaceutical Chemistry	2005	188
Peptide Aldehyde Inhibitors of Cathepsin K Inhibit Bone Resorption Both In Vitro and In Vivo Bartholomew J. Votta, Mark A. Levy, Alison M. Badger, Journal of Bone and Mineral Research SclerostinBiochemistryBone Morphogenic ProteinMedicineNatural Sciences	1997	185
A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys Sanjay Kumar, Lauren Dare, Janice A. Vasko-Moser, Bone Animal PhysiologySclerostinBone ResorptionMedicinePhysiology	2006	136
Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, x-ray crystallography, and infected T-cell assays Geoffrey B. Dreyer, Dennis M. Lambert, Thomas D. Meek, Biochemistry X-ray CrystallographyMolecular BiologyAntiviral DrugChemical BiologyEnzyme Kinetics	1992	128
Design of potent and selective human cathepsin K inhibitors that span the active site Scott K. Thompson, Stacie M. Halbert, Mary J. Bossard, Proceedings of the National Academy of Sciences Bioorganic ChemistryAldo-keto ReductaseMolecular BiologyChemical BiologyMedicinal Chemistry	1997	119

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