Shigeru Sasaki

Integration of interferon-α/β signalling to p53 responses in tumour suppression and antiviral defence

Akinori Takaoka, Sumio Hayakawa, Hideyuki Yanai et al. · Nature · 2003 · 838 citations · Full text

Medicine, Viral Immunity, Immunology +10

Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 σ gene in human hepatocellular carcinoma

Norikazu Iwata, Hiroyuki Yamamoto, Shigeru Sasaki et al. · Oncogene · 2000 · 229 citations

Epigenetic Regulation, Medicine, Natural Sciences +11

Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer

Masanori Nojima, Hiromu Suzuki, M Toyota et al. · Oncogene · 2007 · 227 citations

Sfrp Genes, Systems Biology, Signaling Pathway +8

Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors

Hironobu Sato, Hiromu Suzuki, Minoru Toyota et al. · Carcinogenesis · 2007 · 213 citations

Genetics, Pathology, Human Gastrointestinal Tumors +18

Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability.

Hiroyuki Yamamoto, Fumio Itoh, Hiroyuki Nakamura et al. · PubMed · 2001 · 181 citations

Pancreatic Cancer, Somatic Variant, Frameshift Mutations +14