Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 σ gene in human hepatocellular carcinoma

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

Stephen B. Baylln, James G. Herman, Jeremy R. Graff et al. · Advances in cancer research · 1997 · 1.9K citations

Medicine, Genetics, Oncology +14

Is a p53-Regulated Inhibitor of G2/M Progression

Heiko Hermeking, Christoph Lengauer, Kornélia Polyák et al. · Molecular Cell · 1997 · 1.2K citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Aberrant methylation of <i>p16</i> ^INK4a is an early event in lung cancer and a potential biomarker for early diagnosis

Steven A. Belinsky, Kristen J. Nikula, William A. Palmisano et al. · Proceedings of the National Academy of Sciences · 1998 · 962 citations · Full text

Medicine, Genetics, Molecular Biology +17

14-3-3σ is required to prevent mitotic catastrophe after DNA damage

Timothy A. Chan, Heiko Hermeking, Christoph Lengauer et al. · Nature · 1999 · 890 citations

Life Sciences, Cell Biology, Molecular Biology +12