Wendy R. Irving

Selective Plasma Hydrolysis of Glucocorticoid γ-Lactones and Cyclic Carbonates by the Enzyme Paraoxonase: An Ideal Plasma Inactivation Mechanism

Keith Biggadike, Richard Angell, Colin M. Burgess et al. · Journal of Medicinal Chemistry · 1999 · 180 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +10

The discovery of GSK221149A: A potent and selective oxytocin antagonist

John Liddle, Michael Allen, Alan D. Borthwick et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 92 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

2,5-Diketopiperazines as potent and selective oxytocin antagonists 1: identification, stereochemistry and initial SAR

Paul G. Wyatt, Michael Allen, Alan D. Borthwick et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 66 citations

Medicine, Medicinal Chemistry, Pharmacology +9

Novel Glucocorticoid Antedrugs Possessing a 17β-(γ-Lactone) Ring

Panayiotis A. Procopiou, Keith Biggadike, Alan F. English et al. · Journal of Medicinal Chemistry · 2001 · 56 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +13

2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists. 3. Synthesis, Pharmacokinetics, and in Vivo Potency

Alan D. Borthwick, Dave E. Davies, Anne M. Exall et al. · Journal of Medicinal Chemistry · 2006 · 44 citations

Pharmacy, Pharmacokinetics, Pharmacology +13