Anne M. Exall

The discovery of GSK221149A: A potent and selective oxytocin antagonist

John Liddle, Michael Allen, Alan D. Borthwick et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 90 citations · Full text

Selective Oxytocin, Medicinal Chemistry, Biochemistry +9

Pyridyl-2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists: Synthesis, Pharmacokinetics, and In Vivo Potency

Alan D. Borthwick, John Liddle, Dave E. Davies et al. · Journal of Medicinal Chemistry · 2012 · 89 citations · Full text

Design and Synthesis of Pyrrolidine-5,5-<i>trans-</i>lactams (5-Oxohexahydropyrrolo[3,2-<i>b</i>]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 2. Potency and Chirality

Alan D. Borthwick, Andrew J. Crame, Peter Ertl et al. · Journal of Medicinal Chemistry · 2001 · 72 citations · Full text

Hcmv Deltaala Protease, Bioorganic Chemistry, Novel Mechanism-based Inhibitors +17

Design and Synthesis of Pyrrolidine-5,5‘-<i>trans-</i>Lactams (5-Oxo-hexahydropyrrolo[3,2-<i>b</i>]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 4. Antiviral Activity and Plasma Stability

Alan D. Borthwick, Dave E. Davies, Peter Ertl et al. · Journal of Medicinal Chemistry · 2003 · 71 citations · Full text

2,5-Diketopiperazines as potent and selective oxytocin antagonists 1: identification, stereochemistry and initial SAR

Paul G. Wyatt, Michael Allen, Alan D. Borthwick et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 66 citations

Selective Oxytocin, Medicinal Chemistry, Drug Target +10