Michael C. Lewis

A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

Bryan Goodwin, Stacey A. Jones, Roger R. Price et al. · Molecular Cell · 2000 · 1.9K citations · Full text

Signal Transduction, Biochemistry, Biliary Tract +10

A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport

William R. Oliver, Jennifer L. Shenk, Mike R. Snaith et al. · Proceedings of the National Academy of Sciences · 2001 · 1K citations · Full text

Molecular Pharmacology, Metabolic Syndrome, Insulin Signaling +15

Identification of a Chemical Tool for the Orphan Nuclear Receptor FXR

Patrick Maloney, Derek J. Parks, Curt D. Haffner et al. · Journal of Medicinal Chemistry · 2000 · 521 citations · Full text

Altmetric Attention Score, Molecular Biology, Research Triangle Park +19

Identification of a Nonsteroidal Liver X Receptor Agonist through Parallel Array Synthesis of Tertiary Amines

Jon L. Collins, Adam M. Fivush, Michael A. Watson et al. · Journal of Medicinal Chemistry · 2002 · 426 citations · Full text

Combinatorial Chemistry, Pharmacotherapy, Molecular Pharmacology +17

Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

Yang Zhou, Tobias Kaiser, Patrícia Monteiro et al. · Neuron · 2015 · 315 citations · Full text

Mendelian Disorder, Genetic Disorder, Genetics +9