Bryan Goodwin

A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

Bryan Goodwin, Stacey A. Jones, Roger R. Price et al. · Molecular Cell · 2000 · 1.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

Takeshi Inagaki, Mihwa Choi, Antonio Moschetta et al. · Cell Metabolism · 2005 · 1.8K citations · Full text

Life Sciences, Molecular Biology, Physiology +16

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

Jeff L. Staudinger, Bryan Goodwin, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 2001 · 1.4K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +13

St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

Linda B. Moore, Bryan Goodwin, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 2000 · 938 citations

Medicine, Pharmacology, Toxicology +17

Regulation of Multidrug Resistance-associated Protein 2 (ABCC2) by the Nuclear Receptors Pregnane X Receptor, Farnesoid X-activated Receptor, and Constitutive Androstane Receptor

Heidi R. Kast-Woelbern, Bryan Goodwin, Paul T. Tarr et al. · Journal of Biological Chemistry · 2002 · 908 citations · Full text

Medicine, Molecular Biology, Pharmacology +17