Michael A. Watson

A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

Bryan Goodwin, Stacey A. Jones, Roger R. Price et al. · Molecular Cell · 2000 · 1.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

Sean B. Joseph, Elaine McKilligin, Liming Pei et al. · Proceedings of the National Academy of Sciences · 2002 · 939 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Direct and Indirect Mechanisms for Regulation of Fatty Acid Synthase Gene Expression by Liver X Receptors

Sean B. Joseph, Bryan Laffitte, Parthive H. Patel et al. · Journal of Biological Chemistry · 2002 · 764 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Identification of a Nonsteroidal Liver X Receptor Agonist through Parallel Array Synthesis of Tertiary Amines

Jon L. Collins, Adam M. Fivush, Michael A. Watson et al. · Journal of Medicinal Chemistry · 2002 · 434 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

An association between the allele coding for a low activity variant of catechol-O-methyltransferase and the risk for breast cancer.

Jackie A. Lavigne, Kathy J. Helzlsouer, Han Yao Huang et al. · PubMed · 1997 · 285 citations

Medicine, Genetics, Oncology +12