Inga V. Hochheiser

Statistics

Publications

Citations

610

H-Index

Active since

2020

Affiliations

University of Bonn(Current)

University of Tübingen

Queen's University Belfast

Innovation Cluster (Canada)

Inga V. Hochheiser is an author at University of Bonn specializing in life sciences, nod-like receptors, and nlr family pyrin domain-containing 3 inflammasome.

ORCID

Publications per year

2020–2025

Publications

Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3

Inga V. Hochheiser, Michael Pilsl, Gregor Hagelueken et al. · Nature · 2022 · 287 citations

Life Sciences, Immunology, Molecular Biology +14

β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia

Lea L. Friker, Hannah Scheiblich, Inga V. Hochheiser et al. · Cell Reports · 2020 · 194 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation

Inga V. Hochheiser, Heide Behrmann, Gregor Hagelueken et al. · Science Advances · 2022 · 71 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Non-decameric NLRP3 forms an MTOC-independent inflammasome

Maria Mateo Tortola, Inga V. Hochheiser, Jelena Grga et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2023 · 29 citations · Full text

Life Sciences, Cell Biology, Immunology +17

The discovery of novel and potent indazole NLRP3 inhibitors enabled by DNA-encoded library screening

George D. Hartman, Paul S. Humphries, Robert Hughes et al. · Bioorganic & Medicinal Chemistry Letters · 2024 · 16 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

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