Paul S. Humphries

Carbazole-containing sulfonamides and sulfamides: Discovery of cryptochrome modulators as antidiabetic agents

Paul S. Humphries, Ross Bersot, John Kincaid et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 73 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Science +10

Synthesis and SAR of 1,2,3,4-tetrahydroisoquinolin-1-ones as novel G-protein-coupled receptor 40 (GPR40) antagonists

Paul S. Humphries, John W. Benbow, Paul D. Bonin et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 51 citations · Full text

Biochemistry, G Protein-coupled Receptor, Medicine +5

Structure-based design of novel human Pin1 inhibitors (III): Optimizing affinity beyond the phosphate recognition pocket

Chuangxing Guo, Xinjun Hou, Liming Dong et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 49 citations · Full text

Phosphate Recognition Pocket, Drug Target, Biochemistry +8

Carbazole-containing amides and ureas: Discovery of cryptochrome modulators as antihyperglycemic agents

Paul S. Humphries, Ross Bersot, John Kincaid et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 49 citations

Medicinal Chemistry, Biochemistry, Medicine +8

Microwave-assisted synthesis utilizing supported reagents: a rapid and versatile synthesis of 1,5-diarylpyrazoles

Paul S. Humphries, Jennifer M. Finefield · Tetrahedron Letters · 2006 · 47 citations

Natural Sciences, Diversity-oriented Synthesis, Versatile Synthesis +6