Raúl E. Cachau

Ultrahigh resolution drug design I: Details of interactions in human aldose reductase–inhibitor complex at 0.66 Å

Eduardo Howard, Ruslan Sanishvili, Raúl E. Cachau et al. · Proteins Structure Function and Bioinformatics · 2004 · 308 citations · Full text

Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma

Jennifer N. Brudno, Norris Lam, Danielle Vanasse et al. · Nature Medicine · 2020 · 301 citations · Full text

B-cell Lymphoma, Lymphoid Neoplasia, Cancer Immunosurveillance +8

Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.

A M Silva, Angela Lee, Sergei Gulnik et al. · Proceedings of the National Academy of Sciences · 1996 · 276 citations · Full text

Crystal Structure, Protein Assembly, Biochemistry +13

Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.

Eric T. Baldwin, Talapady N. Bhat, Sergei Gulnik et al. · Proceedings of the National Academy of Sciences · 1993 · 273 citations · Full text

Crystal Structure, Cathepsin D, Protein Assembly +18

Inhibition and catalytic mechanism of HIV-1 aspartic protease

Abelardo M. Silva, Raúl E. Cachau, Hing L. Sham et al. · Journal of Molecular Biology · 1996 · 174 citations

Hiv-1 Aspartic Protease, Biochemistry, Human Retrovirus +4