T Cells Genetically Modified to Express an Anti–B-Cell Maturation Antigen Chimeric Antigen Receptor Cause Remissions of Poor-Prognosis Relapsed Multiple Myeloma

Jennifer N. Brudno, Irina Marić, Steven D. Hartman, +18

Journal of Clinical Oncology

Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma

Jennifer N. Brudno, Norris Lam, Danielle Vanasse, +17

Nature Medicine

B-cell LymphomaLymphoid NeoplasiaCancer ImmunosurveillanceImmunologyHematology +6

Long-Duration Complete Remissions of Diffuse Large B Cell Lymphoma after Anti-CD19 Chimeric Antigen Receptor T Cell Therapy

James N. Kochenderfer, Robert Somerville, Tangying Lu, +8

Molecular Therapy

CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2

Liying Chen, Gabriela Alexe, Neekesh V. Dharia, +30

Journal of Clinical Investigation

GliomaCrispr-cas9 ScreenMedicineCancer GenomicsMycn Amplification +12

Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma

Veronica Veschi, Zhihui Liu, Ty C. Voss, +15

Cancer Cell

Epigenetic SirnaEpigenetic ChangeCancer GenomicsCell BiologyTumor Suppressor +6

Anti-BCMA chimeric antigen receptors with fully human heavy-chain-only antigen recognition domains

Norris Lam, Nathan D. Trinklein, Benjamin Buelow, +3

Nature Communications

Development of CAR T Cells Expressing a Suicide Gene Plus a Chimeric Antigen Receptor Targeting Signaling Lymphocytic-Activation Molecule F7

Christina Amatya, Melissa A. Pegues, Norris Lam, +6

Molecular Therapy

Inhibition of <i>STAT3</i> with the Generation 2.5 Antisense Oligonucleotide, AZD9150, Decreases Neuroblastoma Tumorigenicity and Increases Chemosensitivity

Seiichi Odate, Veronica Veschi, Shuang Yan, +3

Clinical Cancer Research

Laser vision: lidar as a transformative tool to advance critical zone science

A. A. Harpold, Jill Marshall, Steve W. Lyon, +19

Hydrology and earth system sciences

CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG

Zhihui Liu, Xiyuan Zhang, Haiyan Lei, +11

Nature Communications