Matthew E. Cockman

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Patrick H. Maxwell, Michael S. Wiesener, Gin-Wen Chang et al. · Nature · 1999 · 5.2K citations

Medicine, Cancer Biology, Oncology +14

Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein

Matthew E. Cockman, Norma Masson, David R. Mole et al. · Journal of Biological Chemistry · 2000 · 1K citations · Full text

Medicine, Biochemistry, Oncology +17

Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

Matthew E. Cockman, David E. Lancaster, Ineke Stolze et al. · Proceedings of the National Academy of Sciences · 2006 · 282 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Tau Accumulation Activates the Unfolded Protein Response by Impairing Endoplasmic Reticulum-Associated Degradation

Jose F. Abisambra, Umesh K. Jinwal, Laura J. Blair et al. · Journal of Neuroscience · 2013 · 272 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Asparaginyl Hydroxylation of the Notch Ankyrin Repeat Domain by Factor Inhibiting Hypoxia-inducible Factor

Mathew L. Coleman, M.A. McDonough, Kirsty S. Hewitson et al. · Journal of Biological Chemistry · 2007 · 221 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16